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Peptide encyclopedia

Explore 109 peptide references, organized by research area. Each profile brings together the molecule’s identity, selected studies, limitations, and source links.

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5-Amino-1MQ

5-Amino-1MQ is a small molecule studied as an inhibitor of nicotinamide N-methyltransferase (NNMT). Its featured evidence concerns cultured adipocytes and obese mice, rather than demonstrated weight loss in people.

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Abaloparatide

Abaloparatide is a bone-forming prescription medicine for osteoporosis. Its clinically relevant outcome is prevention of fractures in appropriately selected patients.

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Adipotide

Adipotide is a peptidomimetic designed to target blood vessels in adipose tissue. Its featured study reported weight-related changes in obese monkeys and also identified kidney effects.

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Afamelanotide

Afamelanotide is an alpha-MSH analogue investigated for photoprotection in erythropoietic protoporphyria (EPP). Melanotan I is a research name associated with this molecule; an implant trial does not verify a retail research vial.

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AHK-Cu

AHK-Cu is a copper complex of the tripeptide alanine-histidine-lysine. It is related to GHK-Cu but is a different molecule. Its featured evidence uses donated human hair follicles and cultured cells, not people using a product.

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AOD-9604

AOD-9604 is a modified fragment of growth hormone investigated for metabolic effects. Animal experiments and the later human obesity program tell different parts of its story.

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ARA-290

ARA-290, also called cibinetide, is an erythropoietin-derived peptide investigated in tissue-protection research. A small clinical pilot examined neuropathy symptoms in people with sarcoidosis.

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Argireline

Argireline is an acetylated hexapeptide used in cosmetics. A short placebo-controlled trial studied a topical formulation for wrinkles around the eyes.

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Bivalirudin

Bivalirudin is a direct thrombin-inhibitor peptide used in procedural anticoagulation. The featured analysis examined patients with ST-elevation myocardial infarction undergoing coronary intervention.

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BPC-157

BPC-157 is a 15-amino-acid research peptide. Selected animal injury studies and a two-person human safety pilot explore different questions; neither establishes treatment benefit for injured patients.

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Bremelanotide

Bremelanotide is a prescription melanocortin agonist studied for a defined form of low sexual desire associated with distress. It is also known as PT-141.

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Cagrilintide

Cagrilintide is an amylin analogue investigated for weight management. Its evidence must be separated from evidence for combinations containing it.

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Calcitonin salmon

Salmon calcitonin is a hormone medicine that reduces bone breakdown. Injectable and nasal preparations have distinct clinical histories and instructions.

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Cerebrolysin

Cerebrolysin is a porcine-brain-derived mixture of peptides and amino acids. In CASTA, the confirmatory combined functional outcome after acute ischemic stroke was neutral.

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CJC-1295

CJC-1295 is a growth-hormone-releasing-hormone analogue. The foundational human trials studied a long-acting preparation and measured endocrine responses.

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Cortistatin

Cortistatin is a neuropeptide family investigated in inflammatory signaling. The selected study used a mouse arthritis model rather than people with rheumatoid arthritis.

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Cosyntropin

Cosyntropin is a synthetic ACTH fragment used in adrenal testing. The selected research paper examined a separate experimental obstetric application after accidental dural puncture.

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Degarelix

Degarelix is a GnRH antagonist used in prostate-cancer hormone therapy. PRONOUNCE examined cardiovascular events against leuprolide but ended before its planned enrollment.

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Desmopressin

Desmopressin is a hormone analogue used in specific water-balance and related conditions. Its effects depend on the formulation and clinical setting.

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Dihexa

Dihexa is a peptidomimetic studied in experimental cognition research. The selected publication assessed behavioral and molecular changes in a mouse model associated with Alzheimer’s disease.

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DSIP

DSIP stands for delta sleep-inducing peptide. The name reflects its research history, while actual sleep outcomes require direct measurement.

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Dulaglutide

Dulaglutide, marketed as Trulicity, is a long-acting GLP-1 receptor agonist used in type 2 diabetes care. Its research includes blood-sugar control and cardiovascular outcomes.

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Efpeglenatide

Efpeglenatide is an exendin-based GLP-1 receptor agonist. AMPLITUDE-O examined cardiovascular and kidney outcomes in a high-risk type 2 diabetes population.

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Elamipretide

Elamipretide targets mitochondrial biology. Its approved product, Forzinity, has a specific Barth syndrome indication rather than a general anti-aging use.

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Enfuvirtide

Enfuvirtide is an HIV fusion inhibitor with historical combination-treatment evidence. MedlinePlus reports that the injection has been discontinued in the United States.

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Epitalon

Epitalon, also spelled Epithalon, appears in telomerase and aging discussions. The selected study concerns cultured cells rather than a lifespan trial.

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Exenatide

Exenatide is an incretin medicine used in type 2 diabetes. Short-acting and extended-release products need to be distinguished when reading evidence.

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Follistatin 344

Follistatin 344 refers to a follistatin precursor isoform. A frequently cited human study delivered an FS344 gene construct using a viral vector; it did not test injections of a supplier’s follistatin protein.

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FOXO4-DRI

FOXO4-DRI is an experimental peptide designed to disrupt an interaction involved in senescent-cell survival. Its widely discussed aging findings come from cell and mouse experiments.

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GHK

GHK is the Gly-His-Lys tripeptide. It is distinct from GHK-Cu, its copper complex. The selected study examined anxiety-like behavior in male rats.

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GHK-Cu

GHK-Cu combines a short peptide with copper. It is discussed in topical skin care and tissue-remodeling research, which should be separated from injection claims.

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Ghrelin

Ghrelin is a peptide hormone involved in appetite signaling. A small human crossover experiment found higher food intake after an acute infusion.

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GHRP-2

GHRP-2 is a synthetic ghrelin-pathway agonist studied for growth-hormone release and eating behavior. Those effects have different practical implications.

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GHRP-6

GHRP-6 is a growth-hormone secretagogue with effects extending beyond a single hormone. Human physiology studies help explain that distinction.

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Glucagon

Glucagon is a hormone medicine used to raise dangerously low blood glucose. It serves a different role from medicines aimed at lowering glucose or weight.

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Glutathione

Glutathione is an endogenous tripeptide involved in redox biology. A six-month oral-supplement trial measured glutathione stores in several body compartments.

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Gonadorelin

Gonadorelin is gonadotropin-releasing hormone. A clinical series studied pulsatile administration in women with hypothalamic amenorrhea, a specific reproductive-hormone disorder.

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HCG

Human chorionic gonadotropin is a glycoprotein hormone involved in reproductive signaling. The featured study compared hormonal approaches in men with hypogonadism seeking to preserve fertility.

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Hexarelin

Hexarelin is a synthetic six-residue growth-hormone secretagogue. The selected early human experiment measured hormone release, rather than muscle gain or injury recovery.

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HGH Fragment 176-191

HGH Fragment 176-191 is a label for a growth-hormone C-terminal fragment. The selected primary paper studied the related 177-191 fragment, so it is background evidence rather than confirmation of the exact 176-191 product.

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Human insulin

Human insulin replaces or supplements insulin activity in diabetes. Different formulations have different onset and duration, making product identity especially important.

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Humanin

Humanin emerged from experiments examining neuronal cell survival. It is a research topic in mitochondrial and neurodegenerative biology, not an established dementia treatment.

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IGF-1 DES

Des(1-3) IGF-1 is an IGF-1 analogue missing its first three amino acids. The featured study examined developing rat neural tissue in culture, rather than athletic performance.

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IGF-1 LR3

IGF-1 LR3 is a modified IGF-1 analogue. A rat experiment assessed intestinal tissue growth and glucose-analogue absorption, rather than bodybuilding outcomes.

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Ipamorelin

Ipamorelin was developed as a growth-hormone secretagogue. Its often-cited selectivity comes from early pharmacology experiments, not a comprehensive human safety program.

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Kisspeptin-10

Kisspeptin-10 is a short active kisspeptin sequence studied in reproductive-hormone regulation. Hormonal responses are a starting point for fertility research.

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Kisspeptin-54

Kisspeptin-54 is a reproductive-signaling peptide studied as an egg-maturation trigger during IVF. It is a distinct form from the shorter kisspeptin-10 already covered in this directory.

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KPV

KPV is a three-amino-acid peptide investigated in intestinal and immune-cell research. Its short sequence does not make clinical efficacy self-evident.

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L-Carnosine

L-Carnosine is a dipeptide investigated in metabolic and cellular research. A small oral-supplement pilot examined insulin and glucose-related measures in adults without diabetes.

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Lanreotide

Lanreotide is a prescription somatostatin analogue used in specific endocrine and neuroendocrine conditions. Its evidence depends on the disease being treated.

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Larazotide

Larazotide is an investigational peptide studied for persistent symptoms in celiac disease. The featured trial kept participants on a gluten-free diet.

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Leuprolide

Leuprolide is a GnRH agonist used to control sex-hormone signaling in several conditions. It belongs to a different pathway from growth-hormone secretagogues.

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Linaclotide

Linaclotide is an orally administered peptide medicine for defined constipation conditions. Its clinical outcomes concern bowel function and associated symptoms.

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Liraglutide

Liraglutide is an incretin medicine with distinct diabetes and weight-management product contexts. Its benefits should be tied to the exact indication and population.

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Lixisenatide

Lixisenatide is a GLP-1 receptor agonist. ELIXA studied cardiovascular safety in people with type 2 diabetes who had recently experienced an acute coronary event.

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LL-37

LL-37 is a human host-defense peptide investigated in wound biology. The selected clinical study tested topical treatment in a defined ulcer population.

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Matrixyl

The Matrixyl ingredient covered here is palmitoylated KTTKS, also known as palmitoyl pentapeptide-4. A split-face study compared a moisturizer containing this ingredient with its base formulation.

Cosmetic ingredients

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Mazdutide

Mazdutide is a dual GLP-1 and glucagon receptor agonist studied for weight management. GLORY-1 tested it in Chinese adults with overweight or obesity.

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Melanotan II

Melanotan II is an experimental melanocortin analogue studied for pigmentation. It is distinct from Melanotan I and other melanocortin medicines.

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MGF

MGF can refer to an IGF-1 splice-product context or a synthetic terminal E-peptide. A primary replication study found no apparent effect of the tested MGF peptides on muscle-cell proliferation or differentiation.

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MK-677

MK-677, or ibutamoren, is a small-molecule ghrelin mimetic. A trial in older adults found increased fat-free mass without an improvement in strength or physical function.

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Modified GRF 1-29

Modified GRF 1-29 is a label used for modified growth-hormone-releasing-factor fragments, often described by sellers as “CJC no DAC.” The selected primary study concerns albumin-binding conjugates rather than a confirmed DAC-free preparation.

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MOTS-c

MOTS-c is a 16-amino-acid peptide studied as a mitochondrial signal. Its metabolic research is frequently discussed alongside exercise and aging.

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N-Acetyl Selank

N-Acetyl Selank is a modified Selank label. The selected clinical report studied parent Selank, not a verified N-acetylated variant; its findings are included as related background.

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NA-Semax Amidate

NA-Semax Amidate describes a Semax variant with terminal modifications. The selected laboratory publication examined acetylated Semax, but does not verify the complete marketed acetylated-and-amidated variant.

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NAD+

NAD+ is a cofactor involved in cellular redox metabolism. A human pilot measured its metabolic fate during infusion; that experiment did not test longevity, cognition, or treatment of a disease.

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Nesfatin-1

Nesfatin-1 is a NUCB2-derived peptide investigated in feeding regulation. Its foundational evidence involved central administration and signaling experiments in rats.

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Neuropeptide Y

Neuropeptide Y is an endogenous signaling peptide involved in feeding circuitry. The selected mouse study examined NPY-related neurons and feeding behavior rather than a clinical peptide treatment.

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Nisotirostide

Nisotirostide is a selective NPY2 receptor agonist investigated as an adjunct to GLP-1 treatment. The selected publication combines laboratory experiments with a small phase 1 human study.

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Octreotide

Octreotide is a somatostatin-related medicine used in specialist endocrine and gastrointestinal care. Immediate- and long-acting preparations have different roles.

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Orexin-A

Orexin-A, also known as hypocretin-1, is a hypothalamic signaling peptide. The foundational paper identified orexin peptides and receptors and studied feeding responses in rats.

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Oxytocin

Oxytocin is a peptide hormone used in supervised obstetric care. Its established clinical context should be separated from popular social or wellness claims.

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P21

P21 is a research-market label that needs sequence confirmation. The selected paper studied the CNTF-derived candidate P021; it is presented as related research rather than proof that every product labeled P21 has that identity.

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PACAP-38

PACAP-38 is a signaling peptide used in migraine-provocation research. The selected clinical study tested whether prior CGRP-pathway treatment prevented a migraine response to a PACAP-38 challenge.

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Pasireotide

Pasireotide is a somatostatin analogue studied in Cushing disease. The selected trial measured cortisol control and reported frequent hyperglycemia-related events.

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PE-22-28

PE-22-28 is a seven-amino-acid peptide designed from spadin, a naturally occurring fragment of the sortilin propeptide. Its published evidence comes from cell-channel experiments and mouse behavior tests, not studies in people.

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PEG-MGF

PEG-MGF is a seller and research term associated with pegylated mechano-growth-factor fragments. Naming in this area can blur several distinct biological materials.

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Pemvidutide

Pemvidutide is a dual GLP-1 and glucagon receptor agonist investigated in metabolic dysfunction-associated steatohepatitis (MASH). Its liver-biopsy outcomes should be separated from weight-loss claims.

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Peptide bioregulators (Khavinson peptides)

Peptide bioregulators are very short synthetic peptides, two to four amino acids long, developed by Vladimir Khavinson and colleagues in St. Petersburg. Each is named for the tissue it was proposed to support. Almost all published research on them comes from that group and its collaborators.

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Peptide YY

Peptide YY is a gut-hormone family involved in feeding regulation. The selected trial studied PYY3-36 alone and with GLP-1; the combined result should not be described as a proven PYY-alone effect.

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Pinealon

Pinealon is a tripeptide investigated in experimental stress-response biology. The selected publication concerns cells under oxidative stress, rather than a clinical memory or dementia trial.

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Plecanatide

Plecanatide is an oral peptide medicine used for chronic idiopathic constipation and IBS with constipation in adults.

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PNC-27

PNC-27 is a laboratory peptide built from part of the p53 tumor-suppressor protein attached to a cell-penetrating sequence. It has been studied in cancer-cell cultures and animal models. It is not an approved or human-tested cancer treatment.

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Pramlintide

Pramlintide is an adjunctive diabetes medicine used with mealtime insulin in selected patients. It does not replace insulin.

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PTD-DBM

PTD-DBM is an experimental motif peptide investigated in Wnt-associated hair-follicle biology. The featured work included human tissue and cells alongside mouse experiments, rather than a controlled human hair-regrowth trial.

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Retatrutide

Retatrutide is a triple-receptor agonist investigated for obesity and related metabolic conditions. Its trial identity differs from unverified coded seller listings.

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Selank

Selank is a research peptide discussed for anxiety-related effects. Its small clinical literature needs careful attention to study design and replication.

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Semaglutide

Semaglutide is an incretin medicine with product-specific uses in diabetes, weight management, and other defined conditions. Brand and formulation matter.

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Semax

Semax is a seven-amino-acid peptide investigated in neurobiological research. The selected study examines responses to experimental brain ischemia.

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Sermorelin

Sermorelin is a growth-hormone-releasing-hormone fragment with a historical pediatric medicine record. That history needs to be distinguished from current wellness marketing.

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Setmelanotide

Setmelanotide is a melanocortin-4 receptor agonist studied in rare genetic forms of obesity. The featured trials enrolled people with POMC or LEPR deficiency, rather than general-population obesity.

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SNAP-8

SNAP-8 is an acetylated octapeptide used in cosmetics. The featured study tested a combination patch with several active ingredients, so its result does not isolate the effect of SNAP-8.

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Survodutide

Survodutide is a dual GLP-1 and glucagon receptor agonist. A 2026 phase 3 publication reports weight outcomes in adults with obesity or overweight without diabetes.

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TB-500

TB-500 is associated with a short thymosin beta-4 fragment. Much of the biology cited in marketing instead concerns the full-length parent peptide.

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Teduglutide

Teduglutide is a peptide medicine for short bowel syndrome with dependence on intravenous nutrition or fluids. It acts in a different pathway from GLP-1 medicines.

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Teriparatide

Teriparatide is a parathyroid-hormone-related medicine used in osteoporosis care. Fracture reduction is a more direct clinical outcome than a bone marker alone.

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Terlipressin

Terlipressin is a vasopressin-related medicine used in a specific hepatorenal-syndrome setting. Its kidney-function results must be considered with the risk of serious respiratory complications.

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Tesamorelin

Tesamorelin is a prescription peptide for excess abdominal fat in HIV-associated lipodystrophy. It is not a general weight-loss medicine.

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Thymalin

Thymalin is a thymus-derived extract or peptide mixture. An older clinical report described long-term outcomes in elderly participants, but the abstract does not establish the methods needed for a firm causal longevity claim.

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Thymopentin

Thymopentin is a synthetic pentapeptide studied as an immunomodulator. A small 1985 randomized trial examined active rheumatoid arthritis.

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Thymosin alpha-1

Thymosin alpha-1, also called thymalfasin, is investigated for immune-related effects. The clinical value of immune modulation depends on the disease and endpoint.

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Thymosin beta-4

Thymosin beta-4 is a full-length 43-residue peptide studied in tissue biology. The selected human study tested an ophthalmic preparation for dry eye, with negative primary endpoints.

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Thymulin

Thymulin is a thymic peptide whose biological activity depends on zinc. The featured human study examined zinc status and thymulin activity; it was not a trial of thymulin injections.

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Tirzepatide

Tirzepatide is a dual-incretin medicine with distinct product and indication contexts. Its clinical-trial material is not interchangeable with a research-use vial.

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Triptorelin

Triptorelin is a GnRH agonist used for hormone suppression in clinical settings. The featured breast-cancer analysis included several ways of achieving ovarian suppression.

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Vasopressin

Arginine vasopressin is a nine-residue hormone involved in water balance and vascular tone. VASST compared vasopressin with norepinephrine in septic shock.

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VIP

Vasoactive intestinal peptide participates in vascular and immune signaling. A large trial of intravenous aviptadil in COVID-19 respiratory failure did not show a significant improvement in its primary outcome.

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Vosoritide

Vosoritide is a C-type natriuretic peptide analogue studied for growth in children with achondroplasia. Its disease-specific evidence does not support height-increase claims for healthy adults.

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Ziconotide

Ziconotide is a venom-derived peptide medicine that blocks N-type calcium channels. Its pain research concerns specialist intrathecal delivery, not a generic injectable recovery peptide.

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