Peps
What is Ipamorelin?
Ipamorelin was developed as a growth-hormone secretagogue. Its often-cited selectivity comes from early pharmacology experiments, not a comprehensive human safety program.
Biological role or research focus
Growth-hormone secretagogue.
Animal selectivity findings should not be read as evidence that all human uses are safe.
Role reference: Ipamorelin, the first selective growth hormone secretagogue. ↗
Names you may encounter
ipamorelin acetate
Search terms can include brands, combinations, or historical names. They are not automatic product equivalents.
- Class / identity
- Peptide growth-hormone secretagogue
- Main research area
- Secretagogue selectivity
- Evidence featured
- Animal / laboratory study
- Source check
- October 4, 2026
Source: Ipamorelin, the first selective growth hormone secretagogue. ↗
Molecular structure
Mechanism & research rationale
It stimulates a growth-hormone-releasing-peptide pathway. Experiments in pigs found less ACTH/cortisol stimulation than with the comparator secretagogues.
Source: Ipamorelin, the first selective growth hormone secretagogue. ↗
Research context & status
The foundational paper supports a pharmacological classification. It does not establish a treatment for adult muscle gain, aging, or recovery, and it did not test common seller combinations.
Source: Ipamorelin, the first selective growth hormone secretagogue. ↗
What does the evidence show?
Selected published evidence, with the population, findings, and limits kept together. These original summaries draw on publication abstracts; they are not a systematic review.
Animal / laboratory study · 1998
Secretagogue pharmacology
Ipamorelin, the first selective growth hormone secretagogue.
- Population / model
- Rat pituitary cells, rats, and pigs.
- Study design
- Hormone-release and receptor-antagonist experiments with other growth-hormone secretagogues as comparators.
- Main finding
- Ipamorelin stimulated growth-hormone release. In pigs, its ACTH/cortisol response was lower than the responses seen with GHRP-2 and GHRP-6.
- Limits & context
- Selectivity in these models is not proof of endocrine safety in people. This paper did not measure human strength, recovery, body composition, or long-term harms.
Source: Ipamorelin, the first selective growth hormone secretagogue. ↗
Human randomized trial · 2014
Postoperative ileus proof-of-concept trial
Did receptor stimulation speed gastrointestinal recovery after bowel surgery?
- Population / model
- 117 patients enrolled after bowel resection; 114 in the safety and modified intention-to-treat populations.
- Study design
- Multicenter, double-blind, placebo-controlled phase 2 trial of intravenous ipamorelin during short postoperative treatment.
- Main finding
- Median time to tolerating a standardized meal was 25.3 hours with ipamorelin and 32.6 hours with placebo (p=0.15). Key and secondary efficacy analyses did not show significant between-group differences.
- How to read it
- A numerically shorter time is not the same as a demonstrated treatment effect. This trial should be retained when assessing claims about the compound.
- Limits & context
- Small proof-of-concept study with varied underlying conditions. This setting, route, and endpoint do not test muscle gain, fat loss, sleep improvement, or long-term use.
Source: Beck et al. · International Journal of Colorectal Disease · 2014 ↗
Read the original paper for methods, adverse events, funding, and conflicts of interest. Publisher access may require a subscription.
Search additional PubMed records ↗New editorial updates
New source discoveries
Links appear automatically. Unreviewed discoveries are not verified medical findings.
Safety & precautions
Safety evidence & remaining uncertainty
FDA notes serious events in a separate intravenous study. Attribution and clinical context matter; absence of certain hormone changes in animals is not proof of human safety.
Source: FDA · Peptide compounding safety concerns ↗
This is not a complete list of contraindications, interactions, or adverse effects. Medicine labels apply to specific products and indications; research-use listings are not interchangeable with approved medicines.
What are people discussing?
No editorial transcript note has been reviewed for this profile yet. Below are the matching video records available for exploration; title and caption matches are not verified claims.
Watch the source discussions
19 matching video records · 2 with captions indexed.
Across the full library, 30 caption files are indexed from 20,199 inventoried videos. Most transcripts remain unreviewed. Select a thumbnail or timestamp to watch inside PepsRadar. Thumbnail images load from YouTube.
Peptide Of The Week
Telehealth vs Research Peptides: The Truth Nobody Tells You | Peptide of the Week Q&A #61 ↗
Captions indexed · Automatic matches need review
Dr. Trevor Bachmeyer
BPC-157: The Forever Peptide I Take Every Single Day - Dr Trevor Bachmeyer ↗
Captions indexed · Automatic matches need review
Biohackingturkey
Ipamorelin Nedir? Seçici Peptit Hakkında Bilmeniz Gerekenler ↗
Title match · Captions not indexed
Biohackingturkey
Ipamorelin Nedir? Yeni Nesil Büyüme Hormonu Hakkında Her Şey ↗
Title match · Captions not indexed
Dr. Jones, DC
AOD & CJC/Ipamorelin are game changers for fat loss ↗
Title match · Captions not indexed
Dr. Jones, DC
AOD & CJC/Ipamorelin are game changers for fat loss ↗
Title match · Captions not indexed
Sources & supplier listings
Listings are grouped by the vendor’s stated identity. Blends and modified derivatives are labeled separately. Inclusion is not a quality assessment or an endorsement.
Ipamorelin (10mg)
BioLongevity Labs · Vendor-labeled research use only
$79.97
Listed in stock · Snapshot 2026-10-04
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
CJC 1295 & Ipamorelin Blend (10mg) (No DAC)
BioLongevity Labs · Vendor-labeled research use only
$99.97
Listed in stock · Snapshot 2026-10-04
Options may vary. Shipping and tax excluded.
Blend ingredients & evidence →
View seller listing ↗Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
Tesamorelin and Ipamorelin (Blend) (8mg)
BioLongevity Labs · Vendor-labeled research use only
$115.00
Listed in stock · Snapshot 2026-10-04
Options may vary. Shipping and tax excluded.
Blend ingredients & evidence →
View seller listing ↗Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
IPAMORELIN (5 mg / 10 mg)
American Peptides · Vendor-labeled research use only
$40.00–$60.00
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
CJC-1295 (NO DAC) + IPAMORELIN (5/5 mg / 10/10 mg)
American Peptides · Vendor-labeled research use only
$90.00–$150.00
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
TESAMORELIN + IPAMORELIN (10 mg / 5 mg)
American Peptides · Vendor-labeled research use only
$140.00
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
Ipamorelin (5 mg / 10 mg)
PSPeptides · Vendor-labeled research use only
$39.99–$49.99
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
CJC no DAC/Ipamorelin Blend 5+5mg (10 mg)
PSPeptides · Vendor-labeled research use only
$65.99
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
Catalog checked 2026-10-04. Seller listings retain their stated intended use. Shops covered: BioLongevity Labs, BioLongevity Supplements, American Peptides, PSPeptides. This is not a market-wide comparison. Affiliate participation does not determine evidence or editorial coverage.
Questions worth asking
- What specific product, route, and research population does the claim refer to?
- Does the source measure an outcome in people, or only a laboratory marker?
- Animal selectivity findings should not be read as evidence that all human uses are safe.
- What adverse effects, uncertainty, and conflicts of interest does the original source report?
Frequently asked questions
Does “selective” mean free of adverse effects?
No. Selectivity describes the measured responses under specific experimental conditions.
Source: Ipamorelin, the first selective growth hormone secretagogue. ↗
Does the paper validate an ipamorelin/CJC blend?
No. A combination needs its own identity, exposure, benefit, and safety evidence.
Source: Ipamorelin, the first selective growth hormone secretagogue. ↗
What does the additional research establish?
A numerically shorter time is not the same as a demonstrated treatment effect. This trial should be retained when assessing claims about the compound. Small proof-of-concept study with varied underlying conditions. This setting, route, and endpoint do not test muscle gain, fat loss, sleep improvement, or long-term use.
Source: Beck et al. · International Journal of Colorectal Disease · 2014 ↗
References & editorial record
- FDA · Compounding safety concerns ↗
- PubMed · Animal and cell pharmacology · PMID 9849822 ↗
- Beck et al. · International Journal of Colorectal Disease · 2014 ↗
Source notes checked 2026-10-04. Original PepsRadar summaries. Not reviewed by a medical professional. Topic grouping is editorial navigation, not a treatment recommendation. Video notes specify which excerpts were reviewed; no full transcripts are published.
PUT THE EVIDENCE IN CONTEXT
Research guides
RESEARCH FIELD GUIDE
CJC-1295 and ipamorelin: a hormone signal is only part of the story
Why GH and IGF-I measurements, product identity, and a negative postoperative trial belong in the same research discussion.
Read the guide →