Peps
What is Ghrelin?
Ghrelin is a peptide hormone involved in appetite signaling. A small human crossover experiment found higher food intake after an acute infusion.
Biological role or research focus
Acute appetite physiology.
An acute study in nine healthy people does not establish a chronic disease benefit, sustained weight change, or effects in cachexia.
Role reference: Ghrelin enhances appetite and increases food intake in humans. · 2001 ↗
Names you may encounter
Acyl ghrelin
Search terms can include brands, combinations, or historical names. They are not automatic product equivalents.
- Class / identity
- Appetite-related peptide hormone
- Research focus
- Acute appetite physiology
- Featured evidence
- Human randomized crossover study
- Source check
- October 4, 2026
Source: Ghrelin enhances appetite and increases food intake in humans. · 2001 ↗
Biology & proposed mechanism
The selected experiment examined ghrelin-associated hunger and feeding responses. Appetite stimulation is different from a weight-loss effect.
Source: Ghrelin enhances appetite and increases food intake in humans. · 2001 ↗
Research context & identity
This profile concerns physiological appetite research, rather than a validated long-term treatment of weight or muscle conditions.
Source: Ghrelin enhances appetite and increases food intake in humans. · 2001 ↗
What does the evidence show?
Selected published evidence, with the population, findings, and limits kept together. These original summaries draw on publication abstracts; they are not a systematic review.
Human randomized crossover study · 2001
Ghrelin infusion and food intake
What did this publication test, and what did it find?
- Population / model
- Nine healthy volunteers.
- Study design
- Double-blind randomized crossover comparison of ghrelin infusion and saline, followed by appetite and buffet-intake measurements.
- Main finding
- Energy intake was approximately 28% higher after ghrelin, and appetite ratings increased. The tested gastric-emptying measure did not change.
- Limits & context
- An acute study in nine healthy people does not establish a chronic disease benefit, sustained weight change, or effects in cachexia.
Source: Ghrelin enhances appetite and increases food intake in humans. · 2001 ↗
Read the original paper for methods, adverse events, funding, and conflicts of interest. Publisher access may require a subscription.
Further reading · 4 additional publication links
Exact-name PubMed search checked 2026-10-04. These records have not been appraised. A name match can include related compounds, combinations, or other formulations; it does not establish safety or benefit.
Biochemistry, Ghrelin. ↗
· 2023 Jan · Study Guide
Ghrelin's Relationship to Blood Glucose. ↗
Endocrinology · 2019 May 1 · Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review
Read available full text ↗
Ghrelin in gastrointestinal disease. ↗
Molecular and cellular endocrinology · 2011 Jun 20 · Journal Article, Research Support, Non-U.S. Gov't, Review
Ghrelin, reward and motivation. ↗
Endocrine development · 2013 · Journal Article, Research Support, Non-U.S. Gov't, Review
New editorial updates
New source discoveries
Links appear automatically. Unreviewed discoveries are not verified medical findings.
Safety & precautions
Safety & what remains unknown
Short physiological follow-up cannot define chronic endocrine or metabolic safety.
Source: Ghrelin enhances appetite and increases food intake in humans. · 2001 ↗
Evidence boundaries
An acute study in nine healthy people does not establish a chronic disease benefit, sustained weight change, or effects in cachexia.
Source: Ghrelin enhances appetite and increases food intake in humans. · 2001 ↗
This is not a complete list of contraindications, interactions, or adverse effects. Medicine labels apply to specific products and indications; research-use listings are not interchangeable with approved medicines.
What are people discussing?
No editorial transcript note has been reviewed for this profile yet. Below are the matching video records available for exploration; title and caption matches are not verified claims.
Watch the source discussions
2 matching video records · 0 with captions indexed.
Across the full library, 30 caption files are indexed from 20,199 inventoried videos. Most transcripts remain unreviewed. Select a thumbnail or timestamp to watch inside PepsRadar. Thumbnail images load from YouTube.
Thomas DeLauer
Keto Dieting | 4 Reasons You Aren't Hungry | Low Carb Diet Effects | Ghrelin and CCK- Thomas DeLauer ↗
Title match · Captions not indexed
Ultimate Human Podcast with Gary Brecka
The 3 Hormones Controlling Your Stress, Cravings & Energy (Cortisol, Leptin, Ghrelin) ↗
Title match · Captions not indexed
Sources & supplier listings
Listings are grouped by the vendor’s stated identity. Blends and modified derivatives are labeled separately. Inclusion is not a quality assessment or an endorsement.
We have not added a supplier for this profile. Missing products and coded listings are not filled with guesses.
Catalog checked 2026-10-04. Seller listings retain their stated intended use. Shops covered: BioLongevity Labs, BioLongevity Supplements, American Peptides, PSPeptides. This is not a market-wide comparison. Affiliate participation does not determine evidence or editorial coverage.
Questions worth asking
- Is ghrelin studied here as an appetite suppressant?
- What material, population, and route were actually studied?
- An acute study in nine healthy people does not establish a chronic disease benefit, sustained weight change, or effects in cachexia.
- What adverse effects, uncertainty, and conflicts of interest does the original source report?
Frequently asked questions
Is ghrelin studied here as an appetite suppressant?
No. The featured experiment reported increased appetite and food intake.
Source: Ghrelin enhances appetite and increases food intake in humans. · 2001 ↗
Does the publication verify a supplier’s product?
No. The tested material and a commercial listing need separate identity and batch checks. A research-use disclaimer does not establish clinical suitability.
Source: Ghrelin enhances appetite and increases food intake in humans. · 2001 ↗
References & editorial record
Source notes checked 2026-10-04. Original PepsRadar summaries. Not reviewed by a medical professional. Topic grouping is editorial navigation, not a treatment recommendation. Video notes specify which excerpts were reviewed; no full transcripts are published.