What is CJC-1295?
CJC-1295 is a growth-hormone-releasing-hormone analogue. The foundational human trials studied a long-acting preparation and measured endocrine responses.
Biological role or research focus
Stimulation of growth hormone and IGF-1.
CJC-1295 with DAC and products called “CJC no DAC” should not be treated as the same study compound.
Names you may encounter
CJC 1295 · CJC1295
Search terms can include brands, combinations, or historical names. They are not automatic product equivalents.
- Class / identity
- Long-acting GHRH analogue
- Main research area
- Growth hormone and IGF-1 signaling
- Evidence featured
- Human pharmacology trials
- Source check
- October 4, 2026
Molecular structure
Mechanism & research rationale
It stimulates the pituitary growth-hormone pathway, followed by increased IGF-1. Prolonged hormone exposure is central to the studied molecule; a similarly named short-acting product is not automatically equivalent.
Research context & status
The studies establish a pharmacodynamic response in healthy adults. They do not establish injury treatment, muscle-building benefit, or an anti-aging indication. Product names containing “no DAC” need separate identity and study checks.
What does the evidence show?
Selected published evidence, with the population, findings, and limits kept together. These original summaries draw on publication abstracts; they are not a systematic review.
Human pharmacology trials · 2006
Long-acting CJC-1295
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.
- Population / model
- Healthy adults aged 21–61.
- Study design
- Two randomized, blinded, placebo-controlled ascending-dose studies lasting 28 and 49 days.
- Main finding
- Mean growth hormone rose two- to tenfold for at least six days; IGF-1 rose 1.5- to threefold for nine to eleven days after a single exposure. The estimated half-life was 5.8–8.1 days.
- Limits & context
- The endpoints were hormone concentrations. These were studies of long-acting CJC-1295, not proof of muscle gain or equivalence to products labeled “CJC no DAC.”
Human physiology study · 2006
Growth-hormone pulsatility after long-acting CJC-1295
Did longer-lasting stimulation preserve the pattern of GH pulses?
- Population / model
- Healthy men aged 20–40 years.
- Study design
- Overnight blood sampling every 20 minutes before and one week after a single administration of the albumin-binding, long-acting CJC-1295 preparation.
- Main finding
- GH pulses persisted. Trough GH increased markedly, while mean GH and IGF-I also increased. Pulse frequency and magnitude were not significantly altered in the reported assessment.
- How to read it
- A change in hormone secretion is a biological measurement. It does not itself show improved strength, injury recovery, body composition, or quality of life.
- Limits & context
- Short physiological follow-up in healthy men. These results concern the long-acting albumin-binding compound and should not be assigned automatically to products called “CJC without DAC.”
Read the original paper for methods, adverse events, funding, and conflicts of interest. Publisher access may require a subscription.
Search additional PubMed records ↗New editorial updates
New source discoveries
Links appear automatically. Unreviewed discoveries are not verified medical findings.
Safety & precautions
Safety evidence & remaining uncertainty
FDA reports cardiovascular reactions and limited clinical data. Small, short trials reporting no serious events cannot rule out uncommon or long-term harms.
Source: FDA · Peptide compounding safety concerns ↗
This is not a complete list of contraindications, interactions, or adverse effects. Medicine labels apply to specific products and indications; research-use listings are not interchangeable with approved medicines.
What are people discussing?
No editorial transcript note has been reviewed for this profile yet. Below are the matching video records available for exploration; title and caption matches are not verified claims.
Watch the source discussions
19 matching video records · 2 with captions indexed.
Across the full library, 30 caption files are indexed from 20,199 inventoried videos. Most transcripts remain unreviewed. Select a thumbnail or timestamp to watch inside PepsRadar. Thumbnail images load from YouTube.

Peptide Of The Week
Telehealth vs Research Peptides: The Truth Nobody Tells You | Peptide of the Week Q&A #61 ↗
Captions indexed · Automatic matches need review

Thomas DeLauer
The Best Peptide to Truly Lose Fat is Not GLP-1, it’s MOTS-C to Boost Mitochondria ↗
Captions indexed · Automatic matches need review

Biohackingturkey
CJC-1295 Nedir? Bilmeniz Gereken Tüm Gerçekler ↗
Title match · Captions not indexed

Biohackingturkey
CJC-1295 Nedir? Yeni Nesil Peptit Hakkında Bilmeniz Gerekenler ↗
Title match · Captions not indexed

Biohackingturkey
CJC-1295 Peptidi: Gerçekler ve Yan Etkiler ↗
Title match · Captions not indexed

Biohackingturkey
CJC-1295 Peptidi: Ne İşe Yarar, Ne Değil? | 45 Saniyede Bilim ↗
Title match · Captions not indexed
Sources & supplier listings
Listings are grouped by the vendor’s stated identity. Blends and modified derivatives are labeled separately. Inclusion is not a quality assessment or an endorsement.
CJC 1295 & Ipamorelin Blend (10mg) (No DAC)
BioLongevity Labs · Vendor-labeled research use only
$99.97
Listed in stock · Snapshot 2026-10-04
Options may vary. Shipping and tax excluded.
Blend ingredients & evidence →
View seller listing ↗Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
CJC-1295 (NO DAC) (10 mg)
American Peptides · Vendor-labeled research use only
$110.00
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
CJC-1295 (NO DAC) + IPAMORELIN (5/5 mg / 10/10 mg)
American Peptides · Vendor-labeled research use only
$90.00–$150.00
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
CJC-1295 (NO DAC) + GHRP-6 (5/5 mg)
American Peptides · Vendor-labeled research use only
$85.00
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
CJC-1295 With DAC (5 mg)
PSPeptides · Vendor-labeled research use only
$49.99
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
CJC-1295 No DAC (5 mg / 10 mg)
PSPeptides · Vendor-labeled research use only
$35.99–$59.99
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
CJC no DAC/Ipamorelin Blend 5+5mg (10 mg)
PSPeptides · Vendor-labeled research use only
$65.99
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
Catalog checked 2026-10-04. Seller listings retain their stated intended use. Shops covered: BioLongevity Labs, BioLongevity Supplements, American Peptides, PSPeptides. This is not a market-wide comparison. Affiliate participation does not determine evidence or editorial coverage.
Questions worth asking
- What specific product, route, and research population does the claim refer to?
- Does the source measure an outcome in people, or only a laboratory marker?
- CJC-1295 with DAC and products called “CJC no DAC” should not be treated as the same study compound.
- What adverse effects, uncertainty, and conflicts of interest does the original source report?
Frequently asked questions
Does the published half-life apply to “CJC no DAC”?
It should not be assumed to. The trial studied long-acting CJC-1295, not every material sold under the CJC name.
Does higher IGF-1 prove better recovery?
No. It is an endocrine response. Recovery, function, and adverse outcomes must be measured separately.
What does the additional research establish?
A change in hormone secretion is a biological measurement. It does not itself show improved strength, injury recovery, body composition, or quality of life. Short physiological follow-up in healthy men. These results concern the long-acting albumin-binding compound and should not be assigned automatically to products called “CJC without DAC.”
References & editorial record
- FDA · Compounding safety concerns ↗
- CJC-1295 trials in healthy adults (2006) ↗
- Ionescu and Frohman · JCEM · 2006 ↗
Source notes checked 2026-10-04. Original PepsRadar summaries. Not reviewed by a medical professional. Topic grouping is editorial navigation, not a treatment recommendation. Video notes specify which excerpts were reviewed; no full transcripts are published.
PUT THE EVIDENCE IN CONTEXT
Research guides
RESEARCH FIELD GUIDE
CJC-1295 and ipamorelin: a hormone signal is only part of the story
Why GH and IGF-I measurements, product identity, and a negative postoperative trial belong in the same research discussion.
Read the guide →
