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Peptide encyclopedia/ CJC-1295
Illustration for CJC-1295

THE PEPSRADAR ENCYCLOPEDIA

CJC-1295

Stimulation of growth hormone and IGF-1

Research topics · Sources checked 2026-10-04

Read the studies ↓Explore the molecule ↗

CJC-1295 AT A GLANCE

The question behind the molecule.

Read findings and limitations ↓
2 selected publicationsContext mattersCJC-1295 with DAC and products called “CJC no DAC” should not be treated as the same study compound.

What is CJC-1295?

CJC-1295 is a growth-hormone-releasing-hormone analogue. The foundational human trials studied a long-acting preparation and measured endocrine responses.

Biological role or research focus

Stimulation of growth hormone and IGF-1.

CJC-1295 with DAC and products called “CJC no DAC” should not be treated as the same study compound.

Role reference: Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. ↗

Names you may encounter

CJC 1295 · CJC1295

Search terms can include brands, combinations, or historical names. They are not automatic product equivalents.

Class / identity
Long-acting GHRH analogue
Main research area
Growth hormone and IGF-1 signaling
Evidence featured
Human pharmacology trials
Source check
October 4, 2026

Source: Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. ↗

Molecular structure

CJC-1295: 2d molecular structure. The DAC-containing CJC-1295 structure is shown. The no-DAC form is a different molecule.⤢ Enlarge 2D
2D molecular structureThe DAC-containing CJC-1295 structure is shown. The no-DAC form is a different molecule.PubChem · CID 91971820 ↗

Mechanism & research rationale

It stimulates the pituitary growth-hormone pathway, followed by increased IGF-1. Prolonged hormone exposure is central to the studied molecule; a similarly named short-acting product is not automatically equivalent.

Source: Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. ↗

Research context & status

The studies establish a pharmacodynamic response in healthy adults. They do not establish injury treatment, muscle-building benefit, or an anti-aging indication. Product names containing “no DAC” need separate identity and study checks.

Source: Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. ↗

What does the evidence show?

Selected published evidence, with the population, findings, and limits kept together. These original summaries draw on publication abstracts; they are not a systematic review.

Human pharmacology trials · 2006

Long-acting CJC-1295

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.

Population / model
Healthy adults aged 21–61.
Study design
Two randomized, blinded, placebo-controlled ascending-dose studies lasting 28 and 49 days.
Main finding
Mean growth hormone rose two- to tenfold for at least six days; IGF-1 rose 1.5- to threefold for nine to eleven days after a single exposure. The estimated half-life was 5.8–8.1 days.
Limits & context
The endpoints were hormone concentrations. These were studies of long-acting CJC-1295, not proof of muscle gain or equivalence to products labeled “CJC no DAC.”

Source: Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. ↗

Human physiology study · 2006

Growth-hormone pulsatility after long-acting CJC-1295

Did longer-lasting stimulation preserve the pattern of GH pulses?

Population / model
Healthy men aged 20–40 years.
Study design
Overnight blood sampling every 20 minutes before and one week after a single administration of the albumin-binding, long-acting CJC-1295 preparation.
Main finding
GH pulses persisted. Trough GH increased markedly, while mean GH and IGF-I also increased. Pulse frequency and magnitude were not significantly altered in the reported assessment.
How to read it
A change in hormone secretion is a biological measurement. It does not itself show improved strength, injury recovery, body composition, or quality of life.
Limits & context
Short physiological follow-up in healthy men. These results concern the long-acting albumin-binding compound and should not be assigned automatically to products called “CJC without DAC.”

Source: Ionescu and Frohman · JCEM · 2006 ↗

Read the original paper for methods, adverse events, funding, and conflicts of interest. Publisher access may require a subscription.

Search additional PubMed records ↗

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Safety & precautions

Safety evidence & remaining uncertainty

FDA reports cardiovascular reactions and limited clinical data. Small, short trials reporting no serious events cannot rule out uncommon or long-term harms.

Source: FDA · Peptide compounding safety concerns ↗

This is not a complete list of contraindications, interactions, or adverse effects. Medicine labels apply to specific products and indications; research-use listings are not interchangeable with approved medicines.

What are people discussing?

No editorial transcript note has been reviewed for this profile yet. Below are the matching video records available for exploration; title and caption matches are not verified claims.

Watch the source discussions

19 matching video records · 2 with captions indexed.

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Sources & supplier listings

Listings are grouped by the vendor’s stated identity. Blends and modified derivatives are labeled separately. Inclusion is not a quality assessment or an endorsement.

Related label · CJC no DAC blend; not the DAC study compound

CJC 1295 & Ipamorelin Blend (10mg) (No DAC)

BioLongevity Labs · Vendor-labeled research use only

$99.97

Listed in stock · Snapshot 2026-10-04
Options may vary. Shipping and tax excluded.

Blend ingredients & evidence →

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Related label · no-DAC version; not the DAC study compound

CJC-1295 (NO DAC) (10 mg)

American Peptides · Vendor-labeled research use only

$110.00

Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.

View seller listing ↗

Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.

Blend · CJC no DAC

CJC-1295 (NO DAC) + IPAMORELIN (5/5 mg / 10/10 mg)

American Peptides · Vendor-labeled research use only

$90.00–$150.00

Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.

View seller listing ↗

Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.

Blend · CJC no DAC

CJC-1295 (NO DAC) + GHRP-6 (5/5 mg)

American Peptides · Vendor-labeled research use only

$85.00

Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.

View seller listing ↗

Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.

Named compound · with DAC

CJC-1295 With DAC (5 mg)

PSPeptides · Vendor-labeled research use only

$49.99

Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.

View seller listing ↗

Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.

Related label · no-DAC version; not the DAC study compound

CJC-1295 No DAC (5 mg / 10 mg)

PSPeptides · Vendor-labeled research use only

$35.99–$59.99

Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.

View seller listing ↗

Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.

Blend · CJC no DAC

CJC no DAC/Ipamorelin Blend 5+5mg (10 mg)

PSPeptides · Vendor-labeled research use only

$65.99

Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.

View seller listing ↗

Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.

Catalog checked 2026-10-04. Seller listings retain their stated intended use. Shops covered: BioLongevity Labs, BioLongevity Supplements, American Peptides, PSPeptides. This is not a market-wide comparison. Affiliate participation does not determine evidence or editorial coverage.

Questions worth asking

  • What specific product, route, and research population does the claim refer to?
  • Does the source measure an outcome in people, or only a laboratory marker?
  • CJC-1295 with DAC and products called “CJC no DAC” should not be treated as the same study compound.
  • What adverse effects, uncertainty, and conflicts of interest does the original source report?

Frequently asked questions

Does the published half-life apply to “CJC no DAC”?

It should not be assumed to. The trial studied long-acting CJC-1295, not every material sold under the CJC name.

Source: Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. ↗

Does higher IGF-1 prove better recovery?

No. It is an endocrine response. Recovery, function, and adverse outcomes must be measured separately.

Source: Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. ↗

What does the additional research establish?

A change in hormone secretion is a biological measurement. It does not itself show improved strength, injury recovery, body composition, or quality of life. Short physiological follow-up in healthy men. These results concern the long-acting albumin-binding compound and should not be assigned automatically to products called “CJC without DAC.”

Source: Ionescu and Frohman · JCEM · 2006 ↗

References & editorial record

Source notes checked 2026-10-04. Original PepsRadar summaries. Not reviewed by a medical professional. Topic grouping is editorial navigation, not a treatment recommendation. Video notes specify which excerpts were reviewed; no full transcripts are published.

PUT THE EVIDENCE IN CONTEXT

Research guides

For research and education only. This page does not provide medical advice, diagnosis, or treatment. Research-only listings are not instructions for human use.

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MOLECULAR ATLAS

CJC-1295

Download illustration ↓Source record ↗
CJC-1295 2d molecular structure

The DAC-containing CJC-1295 structure is shown. The no-DAC form is a different molecule.