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Peptides that flag heart or blood pressure problems

These 30 profiles mention heart or blood pressure problems in their Risks & interactions section, from the FDA label for approved drugs or from published studies for research compounds. Open a profile and read that section to see exactly why.

A peptide that isn't listed may simply have no human safety data, which doesn't make it safe for you. Dashed tags on investigational GLP-1 drugs come from the labels of approved drugs in the same class. Not medical advice: talk to a doctor or pharmacist about your own situation. All peptides · Blood thinners or bleeding problems · Diabetes or blood-sugar medicines · Cancer, now or in the past · Pregnancy or breastfeeding · Kidney problems · Liver problems

Abaloparatide

Abaloparatide is a bone-forming prescription medicine for osteoporosis. Its clinically relevant outcome is prevention of fractures in appropriately selected patients.

Prescription medicines

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Bivalirudin

Bivalirudin is a direct thrombin-inhibitor peptide used in procedural anticoagulation. The featured analysis examined patients with ST-elevation myocardial infarction undergoing coronary intervention.

Prescription medicines

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Bremelanotide

Bremelanotide is a prescription melanocortin agonist studied for a defined form of low sexual desire associated with distress. It is also known as PT-141.

Prescription medicines

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CJC-1295

CJC-1295 is a growth-hormone-releasing-hormone analogue. The foundational human trials studied a long-acting preparation and measured endocrine responses.

Research topics

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Degarelix

Degarelix is a GnRH antagonist used in prostate-cancer hormone therapy. PRONOUNCE examined cardiovascular events against leuprolide but ended before its planned enrollment.

Prescription medicines

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Desmopressin

Desmopressin is a hormone analogue used in specific water-balance and related conditions. Its effects depend on the formulation and clinical setting.

Prescription medicines

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DSIP

DSIP stands for delta sleep-inducing peptide. The name reflects its research history, while actual sleep outcomes require direct measurement.

Research topics

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Efpeglenatide

Efpeglenatide is an exendin-based GLP-1 receptor agonist. AMPLITUDE-O examined cardiovascular and kidney outcomes in a high-risk type 2 diabetes population.

Research topics

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Glucagon

Glucagon is a hormone medicine used to raise dangerously low blood glucose. It serves a different role from medicines aimed at lowering glucose or weight.

Prescription medicines

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Human insulin

Human insulin replaces or supplements insulin activity in diabetes. Different formulations have different onset and duration, making product identity especially important.

Prescription medicines

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Lanreotide

Lanreotide is a prescription somatostatin analogue used in specific endocrine and neuroendocrine conditions. Its evidence depends on the disease being treated.

Prescription medicines

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Leuprolide

Leuprolide is a GnRH agonist used to control sex-hormone signaling in several conditions. It belongs to a different pathway from growth-hormone secretagogues.

Prescription medicines

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Linaclotide

Linaclotide is an orally administered peptide medicine for defined constipation conditions. Its clinical outcomes concern bowel function and associated symptoms.

Prescription medicines

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Liraglutide

Liraglutide is an incretin medicine with distinct diabetes and weight-management product contexts. Its benefits should be tied to the exact indication and population.

Prescription medicines

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Lixisenatide

Lixisenatide is a GLP-1 receptor agonist. ELIXA studied cardiovascular safety in people with type 2 diabetes who had recently experienced an acute coronary event.

Research topics

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Mazdutide

Mazdutide is a dual GLP-1 and glucagon receptor agonist studied for weight management. GLORY-1 tested it in Chinese adults with overweight or obesity.

Research topics

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Melanotan II

Melanotan II is an experimental melanocortin analogue studied for pigmentation. It is distinct from Melanotan I and other melanocortin medicines.

Research topics

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MK-677

MK-677, or ibutamoren, is a small-molecule ghrelin mimetic. A trial in older adults found increased fat-free mass without an improvement in strength or physical function.

Related compounds

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Octreotide

Octreotide is a somatostatin-related medicine used in specialist endocrine and gastrointestinal care. Immediate- and long-acting preparations have different roles.

Prescription medicines

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Oxytocin

Oxytocin is a peptide hormone used in supervised obstetric care. Its established clinical context should be separated from popular social or wellness claims.

Prescription medicines

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Pasireotide

Pasireotide is a somatostatin analogue studied in Cushing disease. The selected trial measured cortisol control and reported frequent hyperglycemia-related events.

Prescription medicines

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Pemvidutide

Pemvidutide is a dual GLP-1 and glucagon receptor agonist investigated in metabolic dysfunction-associated steatohepatitis (MASH). Its liver-biopsy outcomes should be separated from weight-loss claims.

Research topics

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Retatrutide

Retatrutide is a triple-receptor agonist investigated for obesity and related metabolic conditions. Its trial identity differs from unverified coded seller listings.

Investigational

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Survodutide

Survodutide is a dual GLP-1 and glucagon receptor agonist. A 2026 phase 3 publication reports weight outcomes in adults with obesity or overweight without diabetes.

Research topics

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Teduglutide

Teduglutide is a peptide medicine for short bowel syndrome with dependence on intravenous nutrition or fluids. It acts in a different pathway from GLP-1 medicines.

Prescription medicines

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Teriparatide

Teriparatide is a parathyroid-hormone-related medicine used in osteoporosis care. Fracture reduction is a more direct clinical outcome than a bone marker alone.

Prescription medicines

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Terlipressin

Terlipressin is a vasopressin-related medicine used in a specific hepatorenal-syndrome setting. Its kidney-function results must be considered with the risk of serious respiratory complications.

Prescription medicines

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Triptorelin

Triptorelin is a GnRH agonist used for hormone suppression in clinical settings. The featured breast-cancer analysis included several ways of achieving ovarian suppression.

Prescription medicines

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Vasopressin

Arginine vasopressin is a nine-residue hormone involved in water balance and vascular tone. VASST compared vasopressin with norepinephrine in septic shock.

Prescription medicines

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Vosoritide

Vosoritide is a C-type natriuretic peptide analogue studied for growth in children with achondroplasia. Its disease-specific evidence does not support height-increase claims for healthy adults.

Prescription medicines

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