Peps
What is Glutathione?
Glutathione is an endogenous tripeptide involved in redox biology. A six-month oral-supplement trial measured glutathione stores in several body compartments.
Biological role or research focus
Glutathione stores and supplementation research.
Biomarker changes are different from demonstrated disease prevention, improved survival, or broad “detox” benefits.
Role reference: Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. · 2015 ↗
Names you may encounter
GSH · Reduced glutathione
Search terms can include brands, combinations, or historical names. They are not automatic product equivalents.
- Class / identity
- Endogenous antioxidant tripeptide
- Research focus
- Glutathione stores and supplementation research
- Featured evidence
- Human randomized trial
- Source check
- October 4, 2026
Biology & proposed mechanism
The study tested whether oral supplementation changes measured glutathione concentrations. A higher biomarker concentration does not automatically imply prevention or treatment of a disease.
Research context & identity
The featured evidence concerns an oral preparation. It does not establish equivalent outcomes for intravenous, inhaled, or topical products.
What does the evidence show?
Selected published evidence, with the population, findings, and limits kept together. These original summaries draw on publication abstracts; they are not a systematic review.
Human randomized trial · 2015
Oral glutathione and body stores
What did this publication test, and what did it find?
- Population / model
- 54 nonsmoking adults.
- Study design
- Six-month randomized double-blind placebo-controlled oral-supplementation study, with washout measurements.
- Main finding
- Glutathione increased in measured blood and cellular compartments in the supplemented groups and returned toward baseline after washout.
- Limits & context
- Biomarker changes are different from demonstrated disease prevention, improved survival, or broad “detox” benefits.
Read the original paper for methods, adverse events, funding, and conflicts of interest. Publisher access may require a subscription.
Further reading · 4 additional publication links
Exact-name PubMed search checked 2026-10-04. These records have not been appraised. A name match can include related compounds, combinations, or other formulations; it does not establish safety or benefit.
The antioxidant glutathione. ↗
Vitamins and hormones · 2023 · Journal Article, Research Support, Non-U.S. Gov't
Glutathione as a skin-lightening agent and in melasma: a systematic review. ↗
International journal of dermatology · 2025 Jun · Journal Article, Systematic Review
Glutathione. ↗
The arabidopsis book · 2011 · Journal Article
Read available full text ↗
Glutathione and peroxisome redox homeostasis. ↗
Redox biology · 2023 Nov · Journal Article, Review, Research Support, Non-U.S. Gov't
Read available full text ↗
New editorial updates
New source discoveries
Links appear automatically. Unreviewed discoveries are not verified medical findings.
Safety & precautions
Safety & what remains unknown
Safety and tolerability depend on the route and preparation. Oral findings cannot establish infusion safety.
Evidence boundaries
Biomarker changes are different from demonstrated disease prevention, improved survival, or broad “detox” benefits.
This is not a complete list of contraindications, interactions, or adverse effects. Medicine labels apply to specific products and indications; research-use listings are not interchangeable with approved medicines.
What are people discussing?
No editorial transcript note has been reviewed for this profile yet. Below are the matching video records available for exploration; title and caption matches are not verified claims.
Watch the source discussions
25 matching video records · 7 with captions indexed.
Across the full library, 30 caption files are indexed from 20,199 inventoried videos. Most transcripts remain unreviewed. Select a thumbnail or timestamp to watch inside PepsRadar. Thumbnail images load from YouTube.
MAKE Wellness Official
The Peptide PhDs Podcast: The Truth about Collagen ↗
Captions indexed · Automatic matches need review
Mind Pump Show
Hormones, Peptides & Body Transformation with Phil Vella CEO of Vita Bella Health | Mind Pump 2882 ↗
Captions indexed · Automatic matches need review
Peptide Of The Week
Peptide of the Week: Epithalon & Glutathione – Longevity, Sleep & Detox ↗
Captions indexed · Automatic matches need review
Peptide Of The Week
Peptide of the Week: Gut Health Deep Dive With Liz Roman, The Poop Queen ↗
Captions indexed · Automatic matches need review
Peptide Of The Week
Peptide Q&A #59 – Warrior-Makers Wellness Center, HGH for Women & FOX-O4 vs Fasting ↗
Captions indexed · Automatic matches need review
Peptide Of The Week
Telehealth vs Research Peptides: The Truth Nobody Tells You | Peptide of the Week Q&A #61 ↗
Captions indexed · Automatic matches need review
Sources & supplier listings
Listings are grouped by the vendor’s stated identity. Blends and modified derivatives are labeled separately. Inclusion is not a quality assessment or an endorsement.
L-GLUTATHIONE (600 mg / 1500 mg)
American Peptides · Vendor-labeled research use only
$75.00–$170.00
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
Glutathione (500 mg / 1500 mg)
PSPeptides · Vendor-labeled research use only
$29.99–$69.99
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
Catalog checked 2026-10-04. Seller listings retain their stated intended use. Shops covered: BioLongevity Labs, BioLongevity Supplements, American Peptides, PSPeptides. This is not a market-wide comparison. Affiliate participation does not determine evidence or editorial coverage.
Questions worth asking
- Does this trial prove a detox or disease-prevention benefit?
- What material, population, and route were actually studied?
- Biomarker changes are different from demonstrated disease prevention, improved survival, or broad “detox” benefits.
- What adverse effects, uncertainty, and conflicts of interest does the original source report?
Frequently asked questions
Does this trial prove a detox or disease-prevention benefit?
No. Its principal observations concern glutathione stores and related laboratory measures.
Does the publication verify a supplier’s product?
No. The tested material and a commercial listing need separate identity and batch checks. A research-use disclaimer does not establish clinical suitability.
References & editorial record
Source notes checked 2026-10-04. Original PepsRadar summaries. Not reviewed by a medical professional. Topic grouping is editorial navigation, not a treatment recommendation. Video notes specify which excerpts were reviewed; no full transcripts are published.