Peps
What is 5-Amino-1MQ?
5-Amino-1MQ is a small molecule studied as an inhibitor of nicotinamide N-methyltransferase (NNMT). Its featured evidence concerns cultured adipocytes and obese mice, rather than demonstrated weight loss in people.
Biological role or research focus
NNMT and adipose metabolism.
These experiments do not establish a human weight-loss effect, a clinical regimen, or long-term safety. Different counterions or formulations also need separate identity checks.
Names you may encounter
5-amino-1-methylquinolinium
Search terms can include brands, combinations, or historical names. They are not automatic product equivalents.
- Class / identity
- Small-molecule NNMT inhibitor; not a peptide
- Research focus
- NNMT and adipose metabolism
- Featured evidence
- Animal and cell study
- Source check
- October 4, 2026
Biology & proposed mechanism
The study investigated whether inhibiting NNMT changes cellular metabolite availability and fat synthesis. Target engagement and a mouse response are separate questions from effective human treatment.
Research context & identity
This profile covers preclinical metabolic research. 5-Amino-1MQ is included as a related compound because it appears in peptide catalogs; its chemistry is not peptidic.
What does the evidence show?
Selected published evidence, with the population, findings, and limits kept together. These original summaries draw on publication abstracts; they are not a systematic review.
Animal and cell study · 2018
NNMT inhibition in diet-induced obesity
What did this publication test, and what did it find?
- Population / model
- Cultured adipocytes and mice with high-fat-diet-induced obesity.
- Study design
- Membrane-permeability and enzyme-selectivity experiments followed by metabolic measurements in cells and a short mouse treatment experiment.
- Main finding
- The investigators reported reduced fat synthesis in adipocytes and lower body weight, white-adipose mass, and cholesterol in treated obese mice, without a change in total food intake.
- Limits & context
- These experiments do not establish a human weight-loss effect, a clinical regimen, or long-term safety. Different counterions or formulations also need separate identity checks.
Related NNMT-pathway animal study · 2019
NNMT inhibition · aged muscle injury
What did a separate muscle-regeneration experiment test?
- Population / model
- 24-month-old mice with chemically induced tibialis-anterior injury, plus cultured mouse myoblasts.
- Study design
- Saline versus a small-molecule NNMT inhibitor for one or three weeks; stem-cell activity, muscle-fiber size, and contractile function measured.
- Main finding
- Treated mice showed increased stem-cell proliferation and fusion, larger regenerating fibers, and approximately 70% higher peak torque than controls in the tested muscle.
- How to read it
- This extends NNMT-pathway research beyond the earlier obesity model; it is not a human sarcopenia trial.
- Limits & context
- The abstract names the intervention as NNMTi without stating its exact chemical identity. Compound identity must be checked in the full methods before treating it as direct evidence for a specific 5-amino-1MQ product. Injury-model findings do not establish healthy-human strength or recovery.
Read the original paper for methods, adverse events, funding, and conflicts of interest. Publisher access may require a subscription.
Search additional PubMed records ↗New editorial updates
New source discoveries
Links appear automatically. Unreviewed discoveries are not verified medical findings.
Safety & precautions
Safety & what remains unknown
No observable adverse effects were reported in the short mouse experiment. That observation cannot exclude organ toxicity, interactions, or uncommon harms in people.
Evidence boundaries
These experiments do not establish a human weight-loss effect, a clinical regimen, or long-term safety. Different counterions or formulations also need separate identity checks.
This is not a complete list of contraindications, interactions, or adverse effects. Medicine labels apply to specific products and indications; research-use listings are not interchangeable with approved medicines.
What are people discussing?
No editorial transcript note has been reviewed for this profile yet. Below are the matching video records available for exploration; title and caption matches are not verified claims.
Watch the source discussions
5 matching video records · 1 with captions indexed.
Across the full library, 30 caption files are indexed from 20,199 inventoried videos. Most transcripts remain unreviewed. Select a thumbnail or timestamp to watch inside PepsRadar. Thumbnail images load from YouTube.
Mind Pump Show
Hormones, Peptides & Body Transformation with Phil Vella CEO of Vita Bella Health | Mind Pump 2882 ↗
Captions indexed · Automatic matches need review
Biohackingturkey
5-Amino-1MQ Nedir? Yağ Yakımını Hızlandıran Mucize Molekül ↗
Title match · Captions not indexed
Biohackingturkey
What is 5-amino-1MQ? Effects and Usage ↗
Title match · Captions not indexed
Peptide Of The Week
Peptide of the Week: ARA-290 & 5-Amino-1MQ – Nerve Pain & Fat Burning ↗
Title match · Captions not indexed
Dr. Trevor Bachmeyer
MOTS-C Plus 5-Amino-1MQ a Permanent Answer To Fatigue? Unbreakable Podcast 189 ↗
Title match · Captions not indexed
Sources & supplier listings
Listings are grouped by the vendor’s stated identity. Blends and modified derivatives are labeled separately. Inclusion is not a quality assessment or an endorsement.
5-Amino-1MQ (10mg)
BioLongevity Labs · Vendor-labeled research use only
$74.97
Listed in stock · Snapshot 2026-10-04
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
NAD+ / MOTS-c / 5-Amino-1MQ Blend – 120mg (100mg / 10mg / 10mg)
BioLongevity Labs · Vendor-labeled research use only
$299.99
Listed in stock · Snapshot 2026-10-04
Options may vary. Shipping and tax excluded.
Blend ingredients & evidence →
View seller listing ↗Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
5-AMINO-1MQ (50 mg)
American Peptides · Vendor-labeled research use only
$80.00
Listed out of stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
5Amino-1MQ (5 mg / 10 mg)
PSPeptides · Vendor-labeled research use only
$34.99–$49.99
Listed in stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
Catalog checked 2026-10-04. Seller listings retain their stated intended use. Shops covered: BioLongevity Labs, BioLongevity Supplements, American Peptides, PSPeptides. This is not a market-wide comparison. Affiliate participation does not determine evidence or editorial coverage.
Questions worth asking
- Is 5-Amino-1MQ a peptide?
- What material, population, and route were actually studied?
- These experiments do not establish a human weight-loss effect, a clinical regimen, or long-term safety. Different counterions or formulations also need separate identity checks.
- What adverse effects, uncertainty, and conflicts of interest does the original source report?
Frequently asked questions
Is 5-Amino-1MQ a peptide?
No. It is a small-molecule NNMT inhibitor. Placement in a research-peptide shop does not change its molecular class.
Does the publication verify a supplier’s product?
No. The tested material and a commercial listing need separate identity and batch checks. A research-use disclaimer does not establish clinical suitability.
References & editorial record
Source notes checked 2026-10-04. Original PepsRadar summaries. Not reviewed by a medical professional. Topic grouping is editorial navigation, not a treatment recommendation. Video notes specify which excerpts were reviewed; no full transcripts are published.