Peps
What is PTD-DBM?
PTD-DBM is an experimental motif peptide investigated in Wnt-associated hair-follicle biology. The featured work included human tissue and cells alongside mouse experiments, rather than a controlled human hair-regrowth trial.
Biological role or research focus
Wnt signaling and hair-follicle models.
There was no controlled human treatment trial demonstrating hair restoration in the selected publication.
Role reference: Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis. · 2017 ↗
Names you may encounter
Protein transduction domain–Dishevelled binding motif
Search terms can include brands, combinations, or historical names. They are not automatic product equivalents.
- Class / identity
- Experimental cell-penetrating motif peptide
- Research focus
- Wnt signaling and hair-follicle models
- Featured evidence
- Animal, cell, and human-tissue study
- Source check
- October 4, 2026
Biology & proposed mechanism
The strategy interferes with the CXXC5–Dishevelled interaction in a Wnt-signaling context. Model pathway responses require separate clinical confirmation.
Research context & identity
This profile covers experimental hair and wound-associated follicle research. Human tissue in a laboratory study does not establish a patient treatment result.
What does the evidence show?
Selected published evidence, with the population, findings, and limits kept together. These original summaries draw on publication abstracts; they are not a systematic review.
Animal, cell, and human-tissue study · 2017
CXXC5–Dishevelled interference and hair regeneration
What did this publication test, and what did it find?
- Population / model
- Human scalp tissue and dermal-papilla cells, with mouse genetic and regeneration models.
- Study design
- Mechanistic tissue and cell experiments alongside animal experiments using genetic manipulation and peptide competition.
- Main finding
- The investigators reported changes in Wnt-associated signaling and hair-regrowth or follicle-generation measures in the experimental models.
- Limits & context
- There was no controlled human treatment trial demonstrating hair restoration in the selected publication.
Read the original paper for methods, adverse events, funding, and conflicts of interest. Publisher access may require a subscription.
Further reading · 4 additional publication links
Exact-name PubMed search checked 2026-10-04. These records have not been appraised. A name match can include related compounds, combinations, or other formulations; it does not establish safety or benefit.
CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD(2). ↗
Cells · 2023 Feb 9 · Journal Article, Research Support, Non-U.S. Gov't
Read available full text ↗
Revolutionary Approaches to Hair Regrowth: Follicle Neogenesis, Wnt/ß-Catenin Signaling, and Emerging Therapies. ↗
Cells · 2025 May 26 · Journal Article, Review
Read available full text ↗
Adhesive Hydrogel Patch-Mediated Combination Drug Therapy Induces Regenerative Wound Healing through Reconstruction of Regenerative Microenvironment. ↗
Advanced healthcare materials · 2023 Jul · Journal Article, Research Support, Non-U.S. Gov't
The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing. ↗
The Journal of experimental medicine · 2015 Jun 29 · Journal Article, Research Support, Non-U.S. Gov't
Read available full text ↗
New editorial updates
New source discoveries
Links appear automatically. Unreviewed discoveries are not verified medical findings.
Safety & precautions
Safety & what remains unknown
Changing growth-related signaling requires clinical safety evidence. Laboratory and mouse observations cannot establish safe human hair treatment.
Evidence boundaries
There was no controlled human treatment trial demonstrating hair restoration in the selected publication.
This is not a complete list of contraindications, interactions, or adverse effects. Medicine labels apply to specific products and indications; research-use listings are not interchangeable with approved medicines.
What are people discussing?
No editorial transcript note has been reviewed for this profile yet. Below are the matching video records available for exploration; title and caption matches are not verified claims.
Watch the source discussions
1 matching video records · 0 with captions indexed.
Across the full library, 30 caption files are indexed from 20,199 inventoried videos. Most transcripts remain unreviewed. Select a thumbnail or timestamp to watch inside PepsRadar. Thumbnail images load from YouTube.
Biohackingturkey
Kelliğin Yeni Düşmanı: PTD-DBM Peptidi Nedir? ↗
Title match · Captions not indexed
Sources & supplier listings
Listings are grouped by the vendor’s stated identity. Blends and modified derivatives are labeled separately. Inclusion is not a quality assessment or an endorsement.
We have not added a supplier for this profile. Missing products and coded listings are not filled with guesses.
Catalog checked 2026-10-04. Seller listings retain their stated intended use. Shops covered: BioLongevity Labs, BioLongevity Supplements, American Peptides, PSPeptides. This is not a market-wide comparison. Affiliate participation does not determine evidence or editorial coverage.
Questions worth asking
- Does inclusion of human scalp tissue make this a clinical trial?
- What material, population, and route were actually studied?
- There was no controlled human treatment trial demonstrating hair restoration in the selected publication.
- What adverse effects, uncertainty, and conflicts of interest does the original source report?
Frequently asked questions
Does inclusion of human scalp tissue make this a clinical trial?
No. Studying tissue outside the body is different from treating participants and measuring clinical outcomes.
Does the publication verify a supplier’s product?
No. The tested material and a commercial listing need separate identity and batch checks. A research-use disclaimer does not establish clinical suitability.
References & editorial record
Source notes checked 2026-10-04. Original PepsRadar summaries. Not reviewed by a medical professional. Topic grouping is editorial navigation, not a treatment recommendation. Video notes specify which excerpts were reviewed; no full transcripts are published.