What is Pinealon?
Pinealon is a tripeptide investigated in experimental stress-response biology. The selected publication concerns cells under oxidative stress, rather than a clinical memory or dementia trial.
Biological role or research focus
Oxidative-stress responses in cells.
The study does not establish improved human memory, dementia prevention, or a clinically useful neuroprotective treatment.
Role reference: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗
Names you may encounter
Glu-Asp-Arg · EDR peptide
Search terms can include brands, combinations, or historical names. They are not automatic product equivalents.
- Class / identity
- Glu-Asp-Arg tripeptide
- Research focus
- Oxidative-stress responses in cells
- Featured evidence
- Cell study
- Source check
- October 4, 2026
Biology & proposed mechanism
The investigators measured reactive oxygen species, cell death, and signaling responses. Changing a cell-stress marker is different from demonstrating better cognition in a person.
Research context & identity
The research context includes cerebellar granule cells, neutrophils, and PC12 cells. Findings from these models should remain labeled as laboratory observations.
What does the evidence show?
Selected published evidence, with the population, findings, and limits kept together. These original summaries draw on publication abstracts; they are not a systematic review.
Cell study · 2011
Pinealon under oxidative stress
What did this publication test, and what did it find?
- Population / model
- Cell preparations exposed to experimental oxidative stress.
- Study design
- Laboratory comparisons of cellular stress, viability, ERK signaling, and cell-cycle measures with Pinealon exposure.
- Main finding
- The report described lower reactive oxygen species and necrotic cell death, alongside changes in signaling and cell-cycle responses.
- Limits & context
- The study does not establish improved human memory, dementia prevention, or a clinically useful neuroprotective treatment.
Read the original paper for methods, adverse events, funding, and conflicts of interest. Publisher access may require a subscription.
Further reading · 4 additional publication links
Exact-name PubMed search checked 2026-10-04. These records have not been appraised. A name match can include related compounds, combinations, or other formulations; it does not establish safety or benefit.
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. ↗
Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026 Jan 1 · Journal Article, Review
Read available full text ↗
[Investigation of antihypoxic properties of short peptides]. ↗
Advances in gerontology = Uspekhi gerontologii · 2008 · Journal Article
Pinealon protects the rat offspring from prenatal hyperhomocysteinemia. ↗
International journal of clinical and experimental medicine · 2012 · Journal Article
Read available full text ↗
[EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION]. ↗
Advances in gerontology = Uspekhi gerontologii · 2015 · English Abstract, Journal Article
New editorial updates
New source discoveries
Links appear automatically. Unreviewed discoveries are not verified medical findings.
Safety & precautions
Safety & what remains unknown
Cell viability under one experimental stress condition cannot establish systemic safety or long-term effects.
Evidence boundaries
The study does not establish improved human memory, dementia prevention, or a clinically useful neuroprotective treatment.
This is not a complete list of contraindications, interactions, or adverse effects. Medicine labels apply to specific products and indications; research-use listings are not interchangeable with approved medicines.
What are people discussing?
No editorial transcript note has been reviewed for this profile yet. Below are the matching video records available for exploration; title and caption matches are not verified claims.
Watch the source discussions
6 matching video records · 1 with captions indexed.
Across the full library, 30 caption files are indexed from 20,199 inventoried videos. Most transcripts remain unreviewed. Select a thumbnail or timestamp to watch inside PepsRadar. Thumbnail images load from YouTube.

Peptide Of The Week
Peptide of the Week: Epithalon & Glutathione – Longevity, Sleep & Detox ↗
Captions indexed · Automatic matches need review

Biohackingturkey
Beyin Yaşlanmasını Durduran Peptid: Pinealon Nedir? ↗
Title match · Captions not indexed

Biohackingturkey
Pinealon Peptide: Potential Benefits and Current Evidence ↗
Title match · Captions not indexed

Biohackingturkey
Pinealon Peptidi Nedir? Etkileri ve Bilimsel Gerçekler ↗
Title match · Captions not indexed

Biohackingturkey
Pinealon Peptit Ne İşe Yarar? Beyin ve Hafıza İçin Faydaları ↗
Title match · Captions not indexed

Biohackingturkey
What is Pinealon? Potential Benefits and Usage (A Scientific Perspective) ↗
Title match · Captions not indexed
Sources & supplier listings
Listings are grouped by the vendor’s stated identity. Blends and modified derivatives are labeled separately. Inclusion is not a quality assessment or an endorsement.
PINEALON (20 mg)
American Peptides · Vendor-labeled research use only
$60.00
Listed out of stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.
Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.
Catalog checked 2026-10-04. Seller listings retain their stated intended use. Shops covered: BioLongevity Labs, BioLongevity Supplements, American Peptides, PSPeptides. This is not a market-wide comparison. Affiliate participation does not determine evidence or editorial coverage.
Questions worth asking
- Is this a human cognitive-enhancement trial?
- What material, population, and route were actually studied?
- The study does not establish improved human memory, dementia prevention, or a clinically useful neuroprotective treatment.
- What adverse effects, uncertainty, and conflicts of interest does the original source report?
Frequently asked questions
Is this a human cognitive-enhancement trial?
No. It is a laboratory study of cell responses under oxidative stress.
Does the publication verify a supplier’s product?
No. The tested material and a commercial listing need separate identity and batch checks. A research-use disclaimer does not establish clinical suitability.
References & editorial record
Source notes checked 2026-10-04. Original PepsRadar summaries. Not reviewed by a medical professional. Topic grouping is editorial navigation, not a treatment recommendation. Video notes specify which excerpts were reviewed; no full transcripts are published.
