For research and education only · Not reviewed by a medical professional · Disclaimer · Contains affiliate links

Peptide encyclopedia/ Pinealon
Illustration for Pinealon

THE PEPSRADAR ENCYCLOPEDIA

Pinealon

Oxidative-stress responses in cells

Research topics · Sources checked 2026-10-04

Read the studies ↓

Pinealon AT A GLANCE

The question behind the molecule.

Read findings and limitations ↓
1 selected publicationContext mattersThe study does not establish improved human memory, dementia prevention, or a clinically useful neuroprotective treatment.

What is Pinealon?

Pinealon is a tripeptide investigated in experimental stress-response biology. The selected publication concerns cells under oxidative stress, rather than a clinical memory or dementia trial.

Biological role or research focus

Oxidative-stress responses in cells.

The study does not establish improved human memory, dementia prevention, or a clinically useful neuroprotective treatment.

Role reference: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗

Names you may encounter

Glu-Asp-Arg · EDR peptide

Search terms can include brands, combinations, or historical names. They are not automatic product equivalents.

Class / identity
Glu-Asp-Arg tripeptide
Research focus
Oxidative-stress responses in cells
Featured evidence
Cell study
Source check
October 4, 2026

Source: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗

Biology & proposed mechanism

The investigators measured reactive oxygen species, cell death, and signaling responses. Changing a cell-stress marker is different from demonstrating better cognition in a person.

Source: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗

Research context & identity

The research context includes cerebellar granule cells, neutrophils, and PC12 cells. Findings from these models should remain labeled as laboratory observations.

Source: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗

What does the evidence show?

Selected published evidence, with the population, findings, and limits kept together. These original summaries draw on publication abstracts; they are not a systematic review.

Cell study · 2011

Pinealon under oxidative stress

What did this publication test, and what did it find?

Population / model
Cell preparations exposed to experimental oxidative stress.
Study design
Laboratory comparisons of cellular stress, viability, ERK signaling, and cell-cycle measures with Pinealon exposure.
Main finding
The report described lower reactive oxygen species and necrotic cell death, alongside changes in signaling and cell-cycle responses.
Limits & context
The study does not establish improved human memory, dementia prevention, or a clinically useful neuroprotective treatment.

Source: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗

Read the original paper for methods, adverse events, funding, and conflicts of interest. Publisher access may require a subscription.

Further reading · 4 additional publication links

Exact-name PubMed search checked 2026-10-04. These records have not been appraised. A name match can include related compounds, combinations, or other formulations; it does not establish safety or benefit.

Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. ↗
Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026 Jan 1 · Journal Article, Review
Read available full text ↗

[Investigation of antihypoxic properties of short peptides]. ↗
Advances in gerontology = Uspekhi gerontologii · 2008 · Journal Article

Pinealon protects the rat offspring from prenatal hyperhomocysteinemia. ↗
International journal of clinical and experimental medicine · 2012 · Journal Article
Read available full text ↗

[EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION]. ↗
Advances in gerontology = Uspekhi gerontologii · 2015 · English Abstract, Journal Article

Repeat this PubMed search ↗
Search additional PubMed records ↗

New editorial updates

Loading approved updates…

New source discoveries

Links appear automatically. Unreviewed discoveries are not verified medical findings.

Loading recent discoveries…

Explore the latest source feed →

Safety & precautions

Safety & what remains unknown

Cell viability under one experimental stress condition cannot establish systemic safety or long-term effects.

Source: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗

Evidence boundaries

The study does not establish improved human memory, dementia prevention, or a clinically useful neuroprotective treatment.

Source: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗

This is not a complete list of contraindications, interactions, or adverse effects. Medicine labels apply to specific products and indications; research-use listings are not interchangeable with approved medicines.

What are people discussing?

No editorial transcript note has been reviewed for this profile yet. Below are the matching video records available for exploration; title and caption matches are not verified claims.

Watch the source discussions

6 matching video records · 1 with captions indexed.

Across the full library, 30 caption files are indexed from 20,199 inventoried videos. Most transcripts remain unreviewed. Select a thumbnail or timestamp to watch inside PepsRadar. Thumbnail images load from YouTube.

Sources & supplier listings

Listings are grouped by the vendor’s stated identity. Blends and modified derivatives are labeled separately. Inclusion is not a quality assessment or an endorsement.

Named compound

PINEALON (20 mg)

American Peptides · Vendor-labeled research use only

$60.00

Listed out of stock · Snapshot 2026-10-05
Options may vary. Shipping and tax excluded.

View seller listing ↗

Affiliate link · PepsRadar may earn a commission from purchases through this link. Affiliate disclosure.

Catalog checked 2026-10-04. Seller listings retain their stated intended use. Shops covered: BioLongevity Labs, BioLongevity Supplements, American Peptides, PSPeptides. This is not a market-wide comparison. Affiliate participation does not determine evidence or editorial coverage.

Questions worth asking

  • Is this a human cognitive-enhancement trial?
  • What material, population, and route were actually studied?
  • The study does not establish improved human memory, dementia prevention, or a clinically useful neuroprotective treatment.
  • What adverse effects, uncertainty, and conflicts of interest does the original source report?

Frequently asked questions

Is this a human cognitive-enhancement trial?

No. It is a laboratory study of cell responses under oxidative stress.

Source: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗

Does the publication verify a supplier’s product?

No. The tested material and a commercial listing need separate identity and batch checks. A research-use disclaimer does not establish clinical suitability.

Source: Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. · 2011 ↗

References & editorial record

Source notes checked 2026-10-04. Original PepsRadar summaries. Not reviewed by a medical professional. Topic grouping is editorial navigation, not a treatment recommendation. Video notes specify which excerpts were reviewed; no full transcripts are published.

For research and education only. This page does not provide medical advice, diagnosis, or treatment. Research-only listings are not instructions for human use.

WATCH ON PEPSRADAR

Watch video